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Matsuoka, Hiromitsu; Hashimoto, Kazuyuki; Hishinuma, Yukio*; Ishikawa, Koji*; Terunuma, Hitoshi*; Tatenuma, Katsuyoshi*; Uchida, Shoji*
Journal of Nuclear and Radiochemical Sciences, 6(3), p.189 - 191, 2005/12
Applicability of Mo adsorbent PZC(Poly Zirconium Compound) for W/Re generator was investigated. Long term stability of adsorption of W to the PZC column, elution of Re from PZC column, desorption of from PZC column, and labeling of Hydroxyethylidene Diphosphonic Acid(HEDP) and Mercaptoacetyltriglycine(MAG3) with Re eluted from PZC column were tested. The PZC generator gave reproducible Re elution yields with low W parent breakthrough for a long period of time(about 5 months), that is the W/Re generator using PZC has a potential for practical use.
Hashimoto, Kazuyuki; Wan, K. W. H. B. B.*; Matsuoka, Hiromitsu
Journal of Nuclear and Radiochemical Sciences, 6(3), p.193 - 196, 2005/12
The radioisotopes of rhenium (Re and Re) are attractive radionuclides for radiotherapy because of their energetic beta particles and gamma rays suitable for imaging. Mercaptoacetyltriglycine, MAG3 (NS ligand), is a useful bifunctional ligand in labeling monoclonal antibodies with metallic radionuclides. In this study, the labeling of MAG3 with carrier-free Re from a W/Re generator was investigated in detail. The Re-MAG3 complex was synthesized by the direct labeling method and by the indirect labeling method using a transfer ligand (citric acid or gluconic acid). The dependence of the labeling yield upon the reaction conditions such as the concentrations of tin(II) chloride dihydrate as a reducing agent, S-benzoyl MAG3 and the transfer ligand, pH, temperature, reaction time and the addition of a carrier was examined. The labeling yield of Re-MAG3 synthesized by the all method was over 90% under the optimum conditions.
Hashimoto, Kazuyuki; Matsuoka, Hiromitsu
Radiochimica Acta, 92(4-6), p.285 - 290, 2004/07
Times Cited Count:1 Percentile:9.98(Chemistry, Inorganic & Nuclear)no abstracts in English
Consultative Committee of Research on Radioisotopes
JAERI-Research 2004-001, 117 Pages, 2004/02
no abstracts in English
Ferro-Flores, G.*; Garcia-Salinas, L.*; Paredes-Gutierrez, L.*; Hashimoto, Kazuyuki; Melendes-Alafort, L.*; Murphy, C. A.*
IAEA-TECDOC-1228, p.99 - 103, 2001/06
no abstracts in English
Kobayashi, Katsutoshi; Motoishi, Shoji; Terunuma, Kuzuo; Rauf, A. A.*; Hashimoto, Kazuyuki
Radiochemistry, 42(6), p.551 - 554, 2000/12
no abstracts in English
Hashimoto, Kazuyuki
Radioisotopes, 48(7), p.505 - 506, 1999/07
no abstracts in English
Hashimoto, Kazuyuki
Applied Radiation and Isotopes, 51(3), p.307 - 313, 1999/00
Times Cited Count:12 Percentile:66.07(Chemistry, Inorganic & Nuclear)no abstracts in English
JAERI-Research 98-015, 197 Pages, 1998/03
no abstracts in English
Hashimoto, Kazuyuki; Md.S.Islam*; Izumo, Mishiroku
JAERI-Conf 97-003, p.313 - 317, 1997/03
no abstracts in English
Hashimoto, Kazuyuki; S.Bagiawati*; S.Islam*
Radiochemistry, 39(5), p.389 - 393, 1997/00
no abstracts in English
G.Ferro-Flores*; Hashimoto, Kazuyuki
Radiochimica Acta, 79(1), p.63 - 70, 1997/00
no abstracts in English
Hashimoto, Kazuyuki; S.Bagiawati*; Izumo, Mishiroku; Kobayashi, Katsutoshi
Applied Radiation and Isotopes, 47(2), p.195 - 199, 1996/00
Times Cited Count:23 Percentile:85.69(Chemistry, Inorganic & Nuclear)no abstracts in English
Radioisotopes, 44(2), p.151 - 152, 1995/00
no abstracts in English
Japan-Russia Seminar on Utilization of Radiation and Radioisotopes for Medical Purposes, 0, p.1 - 12, 1994/00
no abstracts in English
; S.Mirzadeh*; R.M.Lambrecht*; R.Knapp*; K.Dadachova*
Radiochimica Acta, 65, p.39 - 46, 1994/00
no abstracts in English